Circadian dependence of manual thrombus aspiration benefit in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.

Clin Res Cardiol. 2018 Apr;107(4):338-346. Fournier S, Muller O, Benedetto U, Roffi M, Pilgrim T, Eberli FR, Rickli H, Radovanovic D, Erne P, Cook S, Noble S, Fesselet R, Zuffi A, Degrauwe S, Masci P, Windecker S, Eeckhout E, Iglesias JF; on behalf on the AMIS Plus Investigators.The clinical benefit of manual thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction (STEMI) remains uncertain. This study assessed the impact of circadian rhythms on the effectiveness of manual TA.